In June 2007, Garcia signed with World Wrestling Entertainment (WWE), and was assigned to Florida Championship Wrestling (FCW), WWE's past developmental territory in Tampa, Florida alongside her twin sister Brie Bella, beginning the tag team The Bella Twins. In November 2008, Garcia debuted on SmackDown as Brianna's "secret" twin. In April 2012, Garcia won the WWE Divas Championship for the first time, making this her first title won with the company, reigning as champion for only a week. In December 2013, both Bella Twins were nominated and awarded Slammy Awards for Divas of the Year. In November 2014, she would win the Divas Championship for a second time, reigning as champion for 301 days, for a combined 307 days, and is now officially recognized as the longest in the title's history. At the same time forming a trio tag team, with Alicia Fox joining both Bellas, dubbing themselves Team Bella. In December 2015, she again won the Slammy Award for Diva of the Year.
Outside of the WWE, Garcia has won many awards, such as ranking No. 1 in Pro Wrestling Illustrated's Female 50 in November 2015, Diva of the Year for Rolling Stone in December 2015, and alongside her sister, would win the award for Choice Female Athlete at the Teen Choice Awards.